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Strength You Can Trust

BioGlue Strength vs. the Competition


In vitro studies show that out of 42 anastomoses, all grafts with BioGlue were able to hold a pressure of 300 mmHg and 10 grafts were tested up to 560 mmHg without leaks.3

Patient Benefits

BioGlue’s mode of action allows it to seal the anastomoses regardless of the patient’s coagulopathic state. BioGlue is especially useful if the native tissue is calcified or fragile, because it will not only seal the anastomosis but also provide reinforcement to the suture line.

Operation Value

BioGlue is a valuable adjunct in numerous cardiac procedures such as Ventricular Assist Device implantation (outflow aortic anastomosis), aortic valve replacement (full root and aortotomies), aneurysm repair, aortic dissection repair and various other large vessel repair.


  • Reapproximates tissue layers together in complex aortic dissection repairs.
  • The adhered layers of a repaired aorta allow for more native tissue to be spared.
  • BioGlue use can reduce the number of reinforcing pledgets used in cardiac repair.1


  • Friable tissues often found in older patients.
  • Weakened tissues in aortic root replacements, aortic valve replacements, dissection repairs, aneurysm repairs, and around aortic cannula sites in VAD implantation.
  • Calcified tissues in repair of abdominal aortic aneurysms, peripheral vessels, and carotid endarterectomies.


  • Works independently of the patient’s coagulopathic state.
  • Seals tissue-graft, tissue-tissue, and graft-graft anastomoses in cardiac and vascular surgery.2
  • Covalent bonding creates a strong seal which gives surgeons the confidence to close.


  1. Coselli J, et al. Prospective Randomized Study of a Protein-Based Tissue Adhesive Used as a Hemostatic
    and Structural Adjunct in Cardiac and Vascular Anastomotic Repair Procedures. J Am Coll Surg 2003; 197:243-253.
  2. CryoLife, Inc. Data on File. PMA #P010003, December 2001.