Aortic Valve Replacement Solutions Heading

No Other Mechanical Valve Has:

  • 90° leaflets:4 promotes laminar flow
  • Pure pyrolytic carbon: reduces thrombogenicity5
  • Flared inlet: organizes flow; prevents pannus

On-X Aortic Valve: INR 1.5-2.0*

  • >60% reduction in bleeding6
  • No increase in thromboembolism (TE)6
  • 2017 AHA/ACC Guidelines: On-X Aortic Valve INR 1.5-2.0 in patients without risk of TE7,*

    *Reduce INR after 3 months standard therapy.4,6
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Advantages of the Ross Procedure Include:

  • No need for lifelong anticoagulation medicine (blood thinner)1
  • Excellent hemodynamic performance (blood flow) at rest and during exercise2,3
  • Only operation shown to restore life expectancy similar to that of the general population1
  • Quality of life similar to those who have not undergone aortic valve replacement1
  • Low risk of thromboembolism (blood clots)1
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MLENG1399.000 (2020-01)

References:

    1. El Hamamsy I, et al. The Lancet 2010;376(9740):524-31.
    2. Pibarot P, et al. Am J Cardiol 2000;86(9):982-8.
    3. Laforest I, et al. Circulation 2002;106:I-57-62.
    4. On-X Prosthetic Heart Valve Instructions for Use, https://www.onxlti.com/ifu/hv/.
    5. LaGrange L, et al. Compatibility of carbon and blood. Hegyeli RJ, Editor, Proceedings, Artificial Heart Program Conference, Washington, DC, June 9-13, 1969, 47-58.
    6. Puskas JD, et al. J Am Coll Cardiol 2018;71:2717-26.
    7. Nishimura R, et al. Circulation 2017;135:e1159-95.