BioGlue® Surgical Adhesive


Burst strength comparison of BioGlue® Surgical Adhesive and ArterX® Surgical Sealant.
                   BioGlue® Surgical Adhesive LVAD Technique.

BioGlue is the leading surgical adhesive in worldwide clinical use for indications in cardiovascular, neurological and soft tissue surgeries. Consisting of purified bovine serum albumin (BSA) and glutaraldehyde, BioGlue has been used in over 1,000,000 surgical procedures in 70 countries since its clinical introduction in 1998. Over 300 BioGlue publications are available for your review.

CryoLife’s BioGlue Syringe is a self-contained, easy-to-use, disposable delivery system. The pre-filled device is available in 2mL, 5mL, and 10mL volumes. BioGlue delivery options include a size range of Standard Applicator Tips, Spreader Tips and Distal Tip Extenders.

The two components are mixed within the applicator tip and dispensed by a controlled delivery system. When cross-linking begins in the applicator tip, BioGlue becomes a protein hydrogel. When applied to the surgical site, BioGlue creates a robust, flexible, mechanical seal independent of the body’s clotting mechanism.


Approved indications for BioGlue vary from country to country. Please verify approved indications in your local language Instructions for Use. In most international markets, BioGlue is indicated for use as an adjunct to standard methods of surgical repair (such as sutures, staples, electrocautery, and/or patches) to bond, seal, and/or reinforce soft tissue. BioGlue may also be applied alone to seal and/or reinforce damaged parenchyma when other ligature or conventional procedures are ineffective or impractical. Indicated soft tissues are:

  • Cardiac
  • Vascular
  • Pulmonary
  • Genitourinary
  • Dural
  • Alimentary (esophageal, gastrointestinal, and colorectal)
  • Abdominal tissues (pancreatic, splenic, hepatic, biliary)

Additionally, BioGlue is used in the fixation of surgical meshes in hernia repair.


Strength Safety Flexibility Friendly
Burst strength to 485 mmHG seals and reinforces tissue Biodegradable and biocompatible Protein hydrogel technology Self-mixing controlled delivery room temp storage-no prep


Please refer to the BioGlue Instructions for Use.


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BioGlue is not approved for commercial distribution in the People’s Republic of China.
BioGlue is approved only for aortic dissection indications in Japan.
BioGlue is indicated in the USA as an adjunct to standard methods of achieving hemostasis in adult patients in open surgical repair of large vessels (such as aorta, femoral, and carotid arteries).