BioFoam™ Mechanism of Action

BioFoam is the reaction product of a protein solution with a cross-linker solution, both containing foaming agents. Upon mixing of the two solutions in the applicator tip both the foaming and crosslinking reactions begin. BioFoam adheres to the tissue and sets up within seconds as a soft foam.

BioFoam has a dual mechanism of action proven to enhance hemostasis by:
• Crosslinking proteins and adhering strongly to tissue, providing a mechanical barrier to decrease blood flow
• Providing pores for blood to enter, leading to cellular aggregation

biofoam-electronscan

BioFoam Application

BioFoam has been proven effective for:
• Sealing abdominal parenchymal tissue which may be prone to post-operative bleeding (e.g. cirrhotic liver)
• A wide range of abdominal surgical procedures including anatomic and extended hemihepatectomies, segmentectomies and enucleations.

biofoam-parenchymal

INDICATIONS FOR USE: BioFoam Surgical Matrix is intended for use as an adjunct when cessation of bleeding by ligature or conventional methods is ineffective or impractical on abdominal parenchymal tissues (liver and spleen).

In the US, BioFoam is approved for investigational use only.

 
Almost all medical devices and products must go through clinical studies and regulatory reviews before they are commercially released, with different countries having different requirements before a product is approved for market. In this section, we have included a number of products that are available in certain countries and not yet available in the United States.